Is creatinine clearance the same as eGFR?

No. Cockcroft-Gault CrCl is an absolute mL/min estimate, while eGFR is usually normalized to 1.73 m2. They can lead to different thresholds in clinical contexts.

Why do some drug labels use Cockcroft-Gault?

Many older drug studies and labels used Cockcroft-Gault CrCl. Current guidance may use CrCl, eGFR or measured kidney function depending on the medication and patient.

Can this diagnose chronic kidney disease?

No. CKD diagnosis depends on persistent findings, albuminuria or other kidney-damage markers and clinical assessment. This is only a calculation aid.

Creatinine Clearance Calculator

Estimate creatinine clearance with the Cockcroft-Gault equation and compare the absolute CrCl result with a BSA-normalized value.

Reference only: this calculator does not diagnose CKD, assess acute kidney injury, or provide medication dosing advice. For medicines, use the drug label and review the result with a clinician or pharmacist.

Sex

Age

Weight, kg

Height, cm

Serum creatinine

Creatinine units

What this creatinine clearance calculator estimates

This tool estimates creatinine clearance using the Cockcroft-Gault equation. CrCl is reported in mL/min as an absolute value, which is different from eGFR normalized to 1.73 m2. Medication labels may use CrCl thresholds, eGFR thresholds or measured kidney function depending on the drug.

CrCl = \frac{( 140 - a g e ) \times w e i g h t _{k g}}{72 \times S c r _{m g / d L}} \times S e x

Cockcroft-Gault creatinine clearance estimate; female sex uses the original 0.85 multiplier.

CrCl_{1.73} = CrCl \times \frac{1.73}{B S A}

Optional normalization for comparison with body-surface-area indexed values.

Not medication dosing advice

Do not start, stop or change medication doses from this calculator. Use the exact drug label and clinician or pharmacist guidance, especially for narrow-therapeutic-index medicines, dialysis, acute kidney injury or unstable creatinine.

CrCl versus eGFR

Measure	Typical unit	Important caveat
Cockcroft-Gault CrCl	mL/min	Absolute estimate often referenced by older drug labels.
eGFR	mL/min/1.73 m2	Normalized estimate used for CKD staging and many lab reports.
Measured clearance	mL/min	May be needed when serum-creatinine estimates are unreliable.

Creatinine-based estimates can be misleading with very high or very low muscle mass, amputation, pregnancy, acute illness, rapidly changing kidney function or unusual diet. In those cases, measured clearance or cystatin C may be considered by clinicians.

Frequently Asked Questions

Sources and References

Calculations are based on the listed reference sources. Links open in a new tab.

Updated: June 2, 2026

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